Antihyperlipidemic Effect of Cholest-4-en-3-one on WHHL Rabbits
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چکیده
منابع مشابه
Cholest-5-en-7-one
In the deca-hydro-phenanthrenone ring system of the title compound, C(27)H(44)O, the two cyclo-hexane rings adopt chair conformations, whereas the cyclo-hexene ring adopts an envelope conformation. The cyclo-pentane ring is twisted. In the crystal structure, mol-ecules are stacked along the a axis, but no significant inter-molecular inter-actions are observed.
متن کاملIdentification and Characterization of TRO19622 (Cholest-4-en-3- One, Oxime), a Novel Drug Candidate for Amyotrophic Lateral Sclerosis
Trophos, Parc Scientifique de Luminy case 931, 13288 Marseille cedex 9, France (T.B., B.B., M.M., C.D., P.G., P.D., E.S., D.M., M.D., R.M.P.) ; Washington University School of Medicine, Saint Louis, MO, USA (N.P.A., A.S.E., D.F.C.); U773 Inserm, Centre de Recherche Biologique Bichat Beaujeon (CRB3), Université Paris 7, Faculté de Médecine Bichat, 16 rue Henri Huchard, BP 416, 75018 Paris, Franc...
متن کاملIdentification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis.
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by progressive death of cortical and spinal motor neurons, for which there is no effective treatment. Using a cell-based assay for compounds capable of preventing motor neuron cell death in vitro, a collection of approximately 40,000 low-molecular-weight compounds was screened to identify potential small-mol...
متن کامل4-(3-Nitrophenyl)-3-(phenylsulfonyl)but-3-en-2-one
The C=C double bond in the title mol-ecule, C(16)H(13)NO(5)S, has an E configuration. The crystal structure is stabilized by C-H⋯O hydrogen bonds. There is also a weak C-H⋯π-ring inter-action in the structure.
متن کاملTriethylammonium O-3β-cholest-5-en-3-yl (4-methoxyphenyl)dithiophosphonate
In the crystal structure of the title compound, C(6)H(16)N(+)·C(34)H(52)O(2)PS(2) (-) or [(CH(3)CH(2))(3)NH](+)·[C(34)H(52)O(2)PS(2)](-), the cation and anion are paired via weak, inter-molecular, bifurcated N-H⋯(S,S) hydrogen bonds. The cholesteryl units form an alternating (herringbone) motif as well as an infinitely stacked layered structure along the b axis. The P-S bond lengths [1.975 (2) ...
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ژورنال
عنوان ژورنال: The Journal of Japan Atherosclerosis Society
سال: 1997
ISSN: 0386-2682,2185-8284
DOI: 10.5551/jat1973.24.12_843